The Trouble with Retinoid Irritation

The Trouble with Retinoid Irritation

Dreaming of smoother, younger-looking skin? Retinoids can help, but don't expect overnight miracles.

Retinoids, are like the superstars of the skincare world. They are Vitamin A derivatives which are clinically proven to combat aging. They work by stimulating collagen production and accelerating cell turnover, leading to smoother, plumper skin.

But being super, does not make it magic! Results do not happen with the wave of a wand and take time. Studies show that consistent use for at least 12 weeks is needed for visible improvements in texture and tone. For the full anti-aging effect, including reduced wrinkles and improved elasticity, be prepared to wait 6 months to a year.

The Secret to Anti-Aging!

Not a secret in the world of dermatology but a game changer for those who tried and abandoned retinoids in the past. The secret?

Consistency is king (or queen) when it comes to retinoids.

Why Consistency?

Regular application maintains the cellular turnover and collagen production needed for long-term skin health. Clinical research confirms this, highlighting the importance of continuous use for significant anti-aging results.

At VETTED Dermlab, we understand the struggle with retinoid irritation. That's why we use hydroxypinacolone (HPR) - a gentler alternative.

Patience and adherence to a regular skincare routine are essential. Applying retinoids consistently helps maintain the steady cellular turnover and collagen production necessary for long-term skin health. Clinical research supports the importance of this regimen, emphasizing that continuous retinoid use results in significant anti-aging effects, such as improved skin elasticity and reduced signs of photoaging₁.

At VETTED Dermlab, we use hydroxypinacolone which allows for anti-aging benefits without the irritation of traditional retinoids.

Here are the main two benefits of taking this approach:

  • Reducing Irritation: Unlike tretinoin, HPR does not require metabolic conversion to retinoic acid. This direct binding minimizes the irritation often associated with the conversion process seen in other retinoids like retinol, which must be converted through a two-step oxidation process (retinol → retinaldehyde → retinoic acid)​₂. 

  • Super for Sensitive Skin: HPR is a milder retinoid, meaning it can produce desired anti-aging effects with less potency, leading to reduced irritation and inflammation. This characteristic makes it suitable for those with sensitive skin.

VETTED Dermlab: Committed to Transparency and Innovation

At VETTED Dermlab, we understand the complexities of navigating the skincare landscape. We prioritize transparency and formulate our products using the gentlest, most effective ingredients backed by scientific evidence.

Our hypoallergenic moisturizers offer intense hydration without relying on petrolatum. Additionally, we are actively researching and incorporating sustainable alternatives into our product lines.

We encourage you to make informed choices based on your unique skin needs and environmental values.

Unlocking Your Skin's Potential: The VETTED Dermlab Difference

By combining the power of science with a commitment to gentle formulations, VETTED Dermlab is here to empower you on your journey to younger-looking skin. We believe in providing effective solutions that are kind to your skin.

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1. Weiss, J. S., Ellis, C. N., Headington, J. T., Tincoff, T., Hamilton, T. A., & Voorhees, J. J. (1988). Topical tretinoin improves photoaged skin: a double-blind vehicle-controlled study. JAMA, 259(4), 527-532.
2. Milosheska D, Roškar R. Use of Retinoids in Topical Antiaging Treatments: A Focused Review of Clinical Evidence for Conventional and Nanoformulations. Adv Ther. 2022;39(12):5351-5375.

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