R Retinoid Serum
R Retinoid Serum
R Retinoid Serum

R Retinoid Serum

VETTED Dermlab R Retinoid Serum is our gentle but powerful anti-aging serum with a unique, non-irritating, retinoid. It is suitable for all skin types and is formulated to be especially safe for sensitive skin.



    Regular price $98.00
    Sale price

      Apply 1-2 pumps to face, neck, and/or chest area at bedtime before VETTED Dermlab M1 or M2Moisturizer.

      R Retinoid Serum insights:

      Designed to combat aging by reducing the appearance of fine lines and uneven pigmentation, our retinoid serum offers a uniquely stable and non-irritating retinoid. We have combined it with squalane to provide maximum efficacy without causing dryness or irritation, even with nightly use.

      Retinoids are potent anti-aging agents because they increase procollagen synthesis and cell differentiation, inhibit melanogenesis, decrease activity of pre-cancerous cells and reduce microcomedones (clogged pores).¹ We use hydroxypinacolone retinoate (HPR) in our anti-aging formula. HPR is more active (as measured in DNA gene transcription and procollagen production), less irritating, and more stable than other non-prescription retinoids. In fact, an in-vitro study found that the pro-collagen synthesis of HPR was equivalent to that of prescription tretinoin (all-trans retinoic acid).2 Additionally, clinical testing found that even at 10X the concentration of other retinoids, HPR was less irritating.² Further, in studies comparing various retinoid formulations, HPR outperformed other retinoids in stability measures like temperature and shelf-life.³

      We add squalane to our retinoid formulation, a powerful emollient that increases cell turnover, improves skin elasticity, reduces the appearance of fine lines and wrinkles, and enhances the skin barrier. 

      Water, Aloe Barbadensis Leaf Juice, Glycerin, Xantham Gum, Glyceryl Stearate, Cetearyl Alcohol, Sodium Stearoyl Lactylate, Caprylic/Capric Triglyceride, Squalane, Isoamyl Laurate, Isoamyl Cocoate, Dimethyl Isosorbide, Hydroxypinacolone Retinoate, Gluconolactone, Lactobacillus Ferment

      Our products are made in the US with ingredients that are vegan, cruelty-free, and responsibly sourced and packaged in recyclable glass and paper. 

      1. Zasada M, Budzisz E. Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments. Postepy Dermatol Alergol. 2019 Aug;36(4):392-397. doi: 10.5114/ada.2019.87443. Epub 2019 Aug 30. PMID: 31616211; PMCID: PMC6791161
      2. Ruth, N., and T. Mammone. "Anti-aging effects of retinoid hydroxypinacolone retinoate on skin models." Journal of Investigative Dermatology 138.5 (2018): S223
      3. Temova Rakuša Ž, Škufca P, Kristl A, Roškar R. Retinoid stability and degradation kinetics in commercial cosmetic products. J Cosmet Dermatol. 2021 Jul;20(7):2 350-2358. doi: 10.1111/jocd.13852. Epub 2020 Dec 2. PMID: 33206444.

      Our products are packaged in recyclable glass and paper.

      Regular price Sold Out
      M2 Rich Moisturizer

      M2 Rich Moisturizer

      M2 Rich Moisturizer is a restorative cream designed for deep moisturization for maximum daytime or nighttime hydration.

      Regular price $86.00
      Sale price

      Find out what makes Vetted, Vetted.

      We are redefining clean. Our ingredients are science-backed, ethically sourced and truly hypoallergenic.

      Our product standards:

      Our formulations were designed by our dermatologists. Every ingredient is carefully selected using the most up-to-date scientific evidence on efficacy, irritant, and allergenic potential.

      We exclude ingredients that are known endocrine disruptors or for which there is credible evidence of concerning health or environmental toxic effects.

      Our products don't have any fragrances or fragrance cross-reactors. 

      We don't include any ingredients that are common (or uncommon, for that matter) causes of allergic contact dermatitis.

      All of our products undergo repeat insult patch testing. There are no reports of irritant or allergic reactions with testing of our formulations. 

      Phthalates are known endocrine disruptors. We don't include any phthalates in our formulations and we package our products in glass (which does not leach phthalates). 

      We do not test any of our formulations on animals. 

      All products are packaged in recyclable glass bottles. 

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